CULTURE OF MYCOBACTERIUM SMEGMATIS IN DIFFERENT CARBON SOURCES TO INDUCE IN VITRO CHOLESTEROL CONSUMPTION LEADS TO ALTERATIONS IN THE HOST CELLS AFTER INFECTION: A MACROPHAGE PROTEOMICS ANALYSIS

During tuberculosis, Mycobacterium uses host macrophage cholesterol as a carbon and energy source.To mimic these conditions, Mycobacterium smegmatis can be cultured in Beach Shorts minimal medium (MM) to induce cholesterol consumption in vitro.During cultivation, M.smegmatis consumes MM cholesterol and changes the accumulation of cell wall compound

As ships become larger, thicker and higher tensile steel plate are used in shipyard.Though special chemical compositions are required for high-tensile steels, recently they are made by the TMCP (Thermo-Mechanical control process) methodology.The increased Yield / Tensile strength of TMCP steels compared to the normalized steel of same composition a

A characteristic feature of modern society is religious pluralism, which is an important factor in the competition between subjects of religious relations, the growth of their influence on each other.Ukrainian society Accessories has never been monoconfessional, and therefore contradictions or even conflicts between denominational communities have

Programmed death ligand 1 (PD-L1) is a co-inhibitory molecule expressed on the surface of various cell types and known for its suppressive effect on T cells through its interaction with PD-1.Neutrophils also express PD-L1, and its expression is elevated in specific situations; however, the immunobiological role of PD-L1+ neutrophils has not been fu